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  • Title: The effect of initial cell concentration on xylose fermentation by Pichia stipitis.
    Author: Agbogbo FK, Coward-Kelly G, Torry-Smith M, Wenger K, Jeffries TW.
    Journal: Appl Biochem Biotechnol; 2007 Apr; 137-140(1-12):653-62. PubMed ID: 18478423.
    Abstract:
    Xylose was fermented using Pichia stipitis CBS 6054 at different initial cell concentrations. A high initial cell concentration increased the rate of xylose utilization, ethanol formation, and the ethanol yield. The highest ethanol concentration of 41.0 g/L and a yield of 0.38 g/g was obtained using an initial cell concentration of 6.5 g/L. Even though more xylitol was produced when the initial cell concentrations were high, cell density had no effect on the final ethanol yield. A two-parameter mathematical model was used to predict the cell population dynamics at the different initial cell concentrations. The model parameters, a and b correlate with the initial cell concentrations used with an R(2) of 0.99.
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