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  • Title: An overview of the fission yeast septation initiation network (SIN).
    Author: Krapp A, Simanis V.
    Journal: Biochem Soc Trans; 2008 Jun; 36(Pt 3):411-5. PubMed ID: 18481970.
    Abstract:
    The fission yeast septation initiation network, or SIN, is a signal transduction network that is required for septum formation in Schizosaccharomyces pombe. Its activity is tightly regulated through the cell cycle, to ensure proper co-ordination of mitosis and cytokinesis. SIN signalling requires three protein kinases for its function and is mediated by a ras-superfamily GTPase. We discuss the elements of the SIN and how they are regulated.
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