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  • Title: [Chronotropic activity of semax].
    Author: Arushanian EB, Popov AV.
    Journal: Eksp Klin Farmakol; 2008; 71(2):14-6. PubMed ID: 18488900.
    Abstract:
    The chronic administration of nootropic drug Semax, a peptide analog of ACTH (4-10), normalized the circadian locomotor rhythm in rats (with an increase in its amplitude, a shift in the acrophase, and a change of the spectral characteristics) and reduced the integral chronobiological index. It is suggested that the rhythm-synchronizing chronotropic activity may be a part of the specific effect of this cognitive enhancer.
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