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  • Title: Outcomes in HIV-infected patients who develop tuberculosis after starting antiretroviral treatment in Malawi.
    Author: Yu JK, Bong CN, Chen SC, Dzimadzi R, Lu DY, Makombe SD, Schouten EJ, Kamoto K, Harries AD.
    Journal: Int J Tuberc Lung Dis; 2008 Jun; 12(6):692-4. PubMed ID: 18492340.
    Abstract:
    A retrospective review was conducted of patients starting antiretroviral treatment (ART) at Mzuzu Central Hospital, Malawi, to identify those who developed tuberculosis (TB) within 6 months of commencing ART and document their treatment outcomes. Of 2933 patients, 22 (0.75%) developed active TB, 17 (77%) of whom had commenced ART as a result of unexplained weight loss and/or fever. Of those who developed TB, 41% successfully completed anti-tuberculosis treatment, with lower survival probabilities than patients who did not develop TB. Easier methods are needed to diagnose TB in human immunodeficiency virus-infected patients and to prevent patients from developing TB while on ART.
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