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  • Title: Pre-operative DTI and probabilisitic tractography in four patients with deep brain stimulation for chronic pain.
    Author: Owen SL, Heath J, Kringelbach M, Green AL, Pereira EA, Jenkinson N, Jegan T, Stein JF, Aziz TZ.
    Journal: J Clin Neurosci; 2008 Jul; 15(7):801-5. PubMed ID: 18495481.
    Abstract:
    This study aimed to examine, using diffusion tensor imaging (DTI), differences in electrode placement in four patients undergoing deep brain stimulation for chronic neuropathic pain of varying aetiology. A pre-operative DTI was obtained for each patient, who was then implanted with deep brain stimulation electrodes in the periventricular/periaqueductal grey area with good pain relief. Using seeds from the postoperative MRI scan, probabilistic tractography was performed from the pre-operative DTI.
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