These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: [Changes of insulin-like growth factor-I in focal cerebral ischemical reperfusion injury in rats].
    Author: Wu HY, Fan JZ, Luo R, Li C, Wei Y.
    Journal: Nan Fang Yi Ke Da Xue Xue Bao; 2008 Apr; 28(4):598-9. PubMed ID: 18495600.
    Abstract:
    OBJECTIVE: To study the changes of insulin-like growth factor-I (IGF-I) in focal cerebral ischemical reperfusion injury model. METHODS: Focal cerebral ischemia was induced in rats using filament method, and the expressions of IGF-I was detected with immunohistochemical staining. RESULTS: The expression of IGF-I was very low in normal brain tissues, but increased in the infracted area and penumbra after cerebral ischemia. The expressions of IGF-I reached the peak level of 14.83-/+0.48 at days 3 after reperfusion. CONCLUSION: Focal cerebral ischemia reperfusion injury enhances the expression of endogenous IGF-I.
    [Abstract] [Full Text] [Related] [New Search]