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  • Title: A case of systemic lupus erythematosus presenting as hypoglycemia due to anti-insulin receptor antibodies.
    Author: Kato Y, Ichiki Y, Kitajima Y.
    Journal: Rheumatol Int; 2008 Nov; 29(1):103-5. PubMed ID: 18500459.
    Abstract:
    We describe herein a patient with hypoglycemia due to anti-insulin receptor antibodies in systemic lupus erythematosus (SLE). A 40-year-old Japanese woman with a 10-year follow-up for SLE was admitted with hypoglycemia. Her blood test revealed the presence of anti-insulin receptor antibody, normal level of insulin and C-peptide, and negative for anti-insulin antibody. Her symptoms responded well to the therapy of predonisolone (30 mg/day) and continuous intravenous glucose as anti-insulin receptor antibody became negative. We emphasize here the significance of these antibodies in complicating the SLE-associated hypoglycemia.
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