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  • Title: In situ hybridization reveals VIP precursor mRNA-containing neurons in monkey and rat neocortex.
    Author: Benson DL, Isackson PJ, Jones EG.
    Journal: Brain Res Mol Brain Res; 1991 Jan; 9(1-2):169-74. PubMed ID: 1850073.
    Abstract:
    The cDNAs encoding monkey vasoactive intestinal polypeptide (VIP) and PHM-27 and rat VIP and PHI-27 were cloned and used to generate antisense RNA probes. Using in situ hybridization, neurons expressing the VIP/PHM or VIP/PHI precursor mRNAs were localized in monkey and rat somatic sensory and visual cortex. In both neocortical areas of both species, labeled cells were observed in all 6 layers as well as the subcortical white matter.
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