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  • Title: Synthesis and structure-activity relationship of aminopyrimidine IKK2 inhibitors.
    Author: Bingham AH, Davenport RJ, Fosbeary R, Gowers L, Knight RL, Lowe C, Owen DA, Parry DM, Pitt WR.
    Journal: Bioorg Med Chem Lett; 2008 Jun 15; 18(12):3622-7. PubMed ID: 18501602.
    Abstract:
    The synthesis and structure-activity relationship of a novel series of aminopyrimidines are exemplified. Results of key compounds from within this series in the E-selectin reporter cell assay are also reported.
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