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Title: Adhesion of sickle red cells to endothelium: myths and future directions. Author: Hebbel RP. Journal: Transfus Clin Biol; 2008; 15(1-2):14-8. PubMed ID: 18501652. Abstract: Sickle RBC are abnormally adherent to vascular endothelial cells. We briefly review the mechanisms that underlie this type of cell/cell adhesion, expose a number of extant myths about RBC adhesion, and discuss some aspects that need consideration via future experimentation. The relationship of this phenomenon of RBC-endothelial adhesion to the cytoadherence of parasitized sickle RBC is not yet clear.[Abstract] [Full Text] [Related] [New Search]