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  • Title: Aqueous extract of Anemarrhena rhizome increases cell proliferation and neuropeptide Y expression in the hippocampal dentate gyrus on streptozotocin-induced diabetic rats.
    Author: Shin MS, Kim SK, Kim YS, Kim SE, Ko IG, Kim YS, Kim CJ, Kim YM, Kim BK, Kim TS.
    Journal: Fitoterapia; 2008 Jul; 79(5):323-7. PubMed ID: 18504079.
    Abstract:
    In this study, the effects of the aqueous extract of Anemarrhena rhizome on cell proliferation and neuropeptide Y expression in the dentate gyrus of streptozotocin-induced diabetic rats were investigated via immunohistochemistry for 5-bromo-2'-deoxyuridine (BrdU) and neuropeptide Y. The results showed that the treatment with 50 to 200 microg/kg/day for 7 days of the aqueous extract of Anemarrhena rhizome increased new cell formation and neuropeptide Y expression in the dentate gyrus of diabetic rats reduced by the treatment with streptozotocin in rat.
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