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  • Title: [Effect of continuous blood purification for management of multiple organ failure with acute renal failure].
    Author: Chen L, Li JH, Jiang Y, Zhu SL, Zhang J.
    Journal: Nan Fang Yi Ke Da Xue Xue Bao; 2008 May; 28(5):896-7. PubMed ID: 18504226.
    Abstract:
    OBJECTIVE: To evaluate the effect of continuous blood purification (CBP) for treatment of multiple organ failure (MOF) with acute renal failure (ARF). METHODS: Forty-seven patients with MOF underwent CBP for an average of 3.1-/+0.5 days averagely. Continuous veno-venous hemofiltration was performed at daytime, and the substitute fluids were infused with pre-dilution at the rate of 2000-4000 ml/h. The general conditions, clinical symptoms, and serum biochemical indexes of the patients were observed and MODS score was calculated. RESULTS: After CBP, the MODS score of the patients decreased significantly from 9.1-/+3.5 to 5.4-/+2.7 (P<0.01) and serum creatinine decreased from 451.3-/+134.5 to 223.7-/+100.2 micromol/L (P<0.05). Twenty-nine patients survived with the survival rate of 61.7%. CONCLUSION: CBP is effective for treatment of MOF and may help reduce the mortality rate of MOF complicated by ARF.
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