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  • Title: [Osteonecrosis of the jaws: a secondary effect of bisphosphonates].
    Author: Schortinghuis J, Meijndert L, De Visscher JG, Witjes MJ.
    Journal: Rev Belge Med Dent (1984); 2007; 62(4):168-75. PubMed ID: 18506991.
    Abstract:
    When treated with intravenous bisphosphonates to prevent bone resorption, 4-10% of the patients may develop osteonecrosis of the jaws a side effect. The osteonecrosis is usually preceded by an invasive dental procedure such as the removal of a tooth. Treatment of the osteonecrosis should be conservative using aseptic mouth rinses, oral antibiotics and small debridement. It seems advisable to have a dental check-up before starting using intravenous bisphosphonates, since a potential dental infections can be treated before the bone healing capacity is reduced by the bisphosphonates.
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