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  • Title: 3H-noradrenaline outflow induced from isolated aventitia and intima-media of rabbit aorta by electrical field stimulation.
    Author: Schrold J, Nedergaard OA.
    Journal: Eur J Pharmacol; 1976 Oct; 39(2):423-7. PubMed ID: 185070.
    Abstract:
    Electrical field stimulation of the isolated adventitial and intima-medial layers of rabbit aorta preloaded with 3H-noradrenaline elicited a 3H outflow. The initial 3H outflow from adventitia was independent of external Ca2+ concentration. Each of the subsequent 3H outflows was mainly Ca2+ sensitive. All stimulation-induced 3H outflows from media were Ca2+ insensitive. It is concluded that the isolated adventitia is a suitable preparation to outflow from aorta is of neuronal and extraneuronal origin.
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