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  • Title: [Synthesis and biological activity of a series of benzopyran derivatives].
    Author: Tang L, Yang YS, Ji RY.
    Journal: Yao Xue Xue Bao; 2008 Feb; 43(2):162-8. PubMed ID: 18507343.
    Abstract:
    Thirteen benzopyran derivatives were synthesized and their activity stimulating the differentiation of preadipocytes into adipocytes were evaluated with 3T3-L1 cells. Compound 8 was also tested for its hypoglycemic activity on db diabetes mice model. Results indicated that compounds 3, 8 and 11 exhibited strong differentiation-stimulating activity on 3T3-L1 cells model, and compound 8 can reduce the blood-sugar level of db diabetes mice dramatically.
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