These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Iron-catalyzed intramolecular o-arylation: synthesis of 2-aryl benzoxazoles.
    Author: Bonnamour J, Bolm C.
    Journal: Org Lett; 2008 Jul 03; 10(13):2665-7. PubMed ID: 18507387.
    Abstract:
    A practical iron-catalyzed intramolecular O-arylation reaction and its application in the synthesis of benzoxazole derivatives, starting from the readily available 2-haloanilines, is presented. The key cyclization step involves the use of a combination of the cheap and environmentally friendly FeCl(3) and 2,2,6,6-tetramethyl-3,5 heptanedione (TMHD) as the catalyst system.
    [Abstract] [Full Text] [Related] [New Search]