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  • Title: Further evidence for "hyper-priming" in thought-disordered schizophrenic patients using repeated masked category priming.
    Author: Wentura D, Moritz S, Frings C.
    Journal: Schizophr Res; 2008 Jul; 102(1-3):69-75. PubMed ID: 18511239.
    Abstract:
    BACKGROUND: Previous research has yielded evidence for enhanced semantic priming in formal thought-disordered schizophrenia patients, a result that fits well with the hypothesis of disinhibited processes of spreading activation in this population. METHODS: The present study tested this hypothesis by using masked repetition priming, which yields reversed semantic priming effects in healthy participants. Assuming that performance in this paradigm relies on a balance between activation and inhibition processes in healthy participants, we compared formal thought-disordered schizophrenia patients, non-thought disordered schizophrenia patients, and healthy controls. RESULTS: For thought-disordered schizophrenia patients, we found a large positive semantic priming effect for dominant category exemplars (primed by the category name), whereas healthy controls had a small negative effect. For non-thought disordered patients, we found a non-significant, numerically positive effect. CONCLUSIONS: This result yields further evidence for the lack of inhibitory processes in thought-disordered patients.
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