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  • Title: [Intracranial spread of a melanoma of the face: the trigeminal pathway].
    Author: Alix T, Boutet C, Caquant L, Mohammedi R, Barral FG, Seguin P.
    Journal: Rev Stomatol Chir Maxillofac; 2008 Jun; 109(3):172-4. PubMed ID: 18513764.
    Abstract:
    INTRODUCTION: The intracranial evolution of cutaneous melanoma is usually due to metastases. Neurotropic invasion mainly concerns the trigeminal and the facial nerves. The melanoma is a rare entity among neurotropic tumors. OBSERVATION: A patient presented with a desmoplastic melanoma of the lower lid, complicated by a perineural extension to the cavernous sinus and the mandibular nerve via the maxillary nerve. DISCUSSION: This neurotropic evolution should be carefully monitored when close to a nerve. Extensive surgical excision including peripheral nerves in the vicinity of such tumors is recommended. MRI should be performed when a motor or sensitive disorder appears in the course of a desmoplastic melanoma.
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