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  • Title: A common polymorphism is associated with body mass index in Uyghur population.
    Author: Zhang J, Lin R, Wang F, Lu M, Lin RY, Wang SZ, Wen H, Jin L, Wang XF.
    Journal: Diabetes Res Clin Pract; 2008 Aug; 81(2):e11-3. PubMed ID: 18514965.
    Abstract:
    We aimed at observing the association of a common genetic variant near the INSIG2 gene (rs7655505) with body mass index (BMI) related obesity in a population-based association study in Uyghur population. We observed a significant association of rs7566605 polymorphism with BMI related obesity in Uyghurs with an odds ratio of 1.47 (95% CI 1.11-1.95, P=0.006) under a dominant model (CC+GC versus GG). The mean BMI of rs7566605 CC+GC was 0.59kg/m(2) higher than for GG genotype (P=0.024), regardless of sex and age.
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