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  • Title: Effects of 250 and 500 Hz tone exposure on the inner ear of guinea pigs as determined by electrophysiological techniques.
    Author: Fujita T, Sugisawa T, Matsui T, Takahashi M, Inada N, Ishida A, Yamamura K.
    Journal: ORL J Otorhinolaryngol Relat Spec; 1991; 53(3):147-52. PubMed ID: 1852412.
    Abstract:
    The electrophysiological study of cochlear microphonics (CM), whole nerve action potential (AP) and endocochlear potential (EP) were examined. (1) With the extension of the exposure time of 500 Hz tone, a decrease of CM maximum output voltage in test frequency from 2 to 6 kHz was observed. (2) N1 potential of AP decreased very significantly by 500 Hz tone exposure. (3) A very pronounced decrease of the absolute value of the negative potential of the EP in 500 Hz exposure was seen.
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