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  • Title: [Change in the content of serum immunoglobulins A, G, M in patients with pulmonary tuberculosis and alcoholism during antibacterial and anti-alcoholism therapy].
    Author: Maskeev KM, Kasenova SL.
    Journal: Probl Tuberk; 1991; (4):57-60. PubMed ID: 1852747.
    Abstract:
    Serum immunoglobulins A, G, M in 93 patients with pulmonary tuberculosis and suffering from alcoholism at the same time (a core group) were investigated in the course of a combined therapy. A control group consisted of 44 pulmonary tuberculosis patients who were nonalcoholics. Examinations were carried out on their admission to a hospital and 3, 6 and 9-12 months after treatment. The findings proved that the patients of the core group had hyperproduction of main serum immunoglobulins. In the course of a complex antibacterial and antialcoholic therapy the IgA values remained high. A disturbed functional activity of B-lymphocytes is likely to be one of the causes leading to a low efficacy of the tuberculosis treatment among alcoholics.
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