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  • Title: A DNA vaccine for the prevention of Ebola virus infection.
    Author: Dery M, Bausch DG.
    Journal: Curr Opin Mol Ther; 2008 Jun; 10(3):285-93. PubMed ID: 18535936.
    Abstract:
    The NIH and Vical Inc are developing an intramuscular needle-free DNA vaccine containing plasmids encoding the envelope glycoprotein of Ebola virus (EBOV) from the Sudan and Zaire strains, and the nucleoprotein of EBOV Zaire strain. A phase I clinical trial demonstrated a good safety profile, with most adverse events limited to the site of injection and largely attributable to the delivery.
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