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  • Title: [Effects of volatile oil of Rhizoma zingiberis and other two kinds of volatile oil on percutaneous penetration of bullatine A via hairless mouse skin in vitro].
    Author: Bai YC, Li YJ, Ma YS.
    Journal: Zhongguo Zhong Yao Za Zhi; 2008 Mar; 33(5):513-6. PubMed ID: 18536371.
    Abstract:
    OBJECTIVE: To investigate the effects of volatile oils of Rhizoma Acori Tatarinowii (RAT), Semen Myristicae (SM) and Pericarpium Citri Reticulatae (PCR) on percutaneous penetration of bullatine A via hairless mouse skin in vitro. METHOD: By an improved Franz diffusion, the effects of three kinds of volatile oils on the percutaneous penetration of bullatine A were observed and compared with Azone, and the cumulative amount of bullatine A was determined by HPLC. RESULT: The penetration enhancement ratios of bullatine A with 7% volatile oil RAT and SM, 5% volatile oil of PCR and 3% Azone were 6.52, 6.74, 2.18, 6.03, respectively. CONCLUSION: The volatile oil of RAT, SM and PCR enhance permeation of bullatine A, effectively.
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