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  • Title: [Systemic metastases of malignant gliomas].
    Author: Fourtassi M, Psimaras D, Ducray F, Sanson M.
    Journal: Bull Cancer; 2008 May; 95(5):522-5. PubMed ID: 18541516.
    Abstract:
    Despite malignant gliomas are highly invasive tumors, extracranial metastatases are extremely rare. We report herein four cases (two glioblastomas, a gliosarcoma and an anaplastic oligodendroglioma) with systemic dissemination occurring 3 to 13 months after surgery. Metastases involved liver, lung, kidney, bone and bone marrow. Survival time after metastatic dissemination ranged from 2 to 5 months for glioblastomas and gliosarcoma. Metastases from the anaplastic oligodendroglioma which displayed 1p and 19q chromosome codeletion, responded to chemotherapy and the patient survived 8 months.
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