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  • Title: [Disturbance of epithelial proliferation of the gastro-intestinal tract mucosa in ulcers and erosion].
    Author: Timoshin SS, Alekseenko SA, Borovskaia TF, Kukovitskiĭ AF.
    Journal: Arkh Patol; 1991; 53(3):37-40. PubMed ID: 1854275.
    Abstract:
    Epithelial proliferation in the mucosa of the gastro-intestinal tract was studied autoradiographically with 3H-thymidine under the following conditions: acute gastric ulcers as complication of acute pancreatitis; exacerbation of duodenal ulcer; ulcers and erosions in bacterial dysentery. Mucosa of practically healthy persons as well as mucosa of patients with the same diseases not complicated with ulcers and erosions served as control. Biopsies of mucosa were taken 2 cm from ulcers and erosions. The decrease of DNA-synthesizing nuclei number in the mucosa epithelium at early stages of ulcer formation was observed in all these conditions.
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