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  • Title: [Spontaneous subarachnoid haemorrhage: a study of 462 patients].
    Author: Parkhutik V, Lago A, Tembl JI, Beltrán A, Fuset MP.
    Journal: Rev Neurol; ; 46(12):705-8. PubMed ID: 18543194.
    Abstract:
    AIMS: To describe the demographic characteristics of patients with spontaneous subarachnoid haemorrhage (SAH) in our population and to compare the endovascular and surgical treatment of intracranial aneurysms. PATIENTS AND METHODS: We conducted a retrospective study of 462 patients who were admitted to the Hospital Universitario La Fe in Valencia between April 1997 and March 2005. RESULTS: The mean age was 56.8 +/- 14.8 years and 55.8% of the patients were females. The risk factors were: arterial hypertension, 40.3%; smoking, 32.7%; dyslipidemia, 16.0%; diabetes mellitus, 10.6%; alcoholism, 6.7%. A cerebral arteriography was performed in 369 patients and intracranial aneurysms were detected in 246 of them. Aneurysms were treated by embolisation in 62.6% of cases and by surgery in 22%. On comparing the embolisation and surgery groups, there were non-significant differences in the rates of complications. Infections were present in 21.9% of patients in the embolisation group versus 10.2% in the surgery group; epileptic seizures 6.1% versus 8%; hydrocephalus 2.7% versus 4%; rebleeding 4.1% versus 10.2%; clinical vasospasm 8.9% versus 6.1%. The rate of sequelae on discharge (a score on the modified Rankin Scale > 3) was 13.7% among surviving patients in the embolisation group and 15.5% in the group that had undergone surgery. The mortality rates in the two groups were 10.3 and 10%, respectively. Overall mortality rate was 30.1%. CONCLUSIONS: The presentation and course of SAH in our population follow a pattern that is similar to those reported in other countries. No differences in morbidity and mortality were detected between the endovascular and surgical treatment of ruptured intracranial aneurysms.
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