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  • Title: [Using solutions of hydroxyethyl starch (6% HES 200/0.5 (refortan) and 6% HES 130/0.4 (voluven)) in neuroanesthesiology].
    Author: Kondrat'ev AN, Novikov VIu, Savvina IA, Driagina NV.
    Journal: Anesteziol Reanimatol; 2008; (2):27-30. PubMed ID: 18543426.
    Abstract:
    The paper provides the results of a complex experimental and clinical study of the effects of infusion solutions of hydroxyethyl starch (HES 200/0.5--Refortan and HES 130/0.4--Voluven) on hemostatic and systemic hemodynamic parameters in patients operated on for neurosurgical pathology of the brain. The HES solutions are shown to have a more pronounced volemic effect and a slightly higher hypocoagulation effect on the hemostatic system (as compared with physiological solution); the latter does not, however, achieve its clinical value with the used doses of the solutions.
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