These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Full-range, high-speed, high-resolution 1 microm spectral-domain optical coherence tomography using BM-scan for volumetric imaging of the human posterior eye.
    Author: Makita S, Fabritius T, Yasuno Y.
    Journal: Opt Express; 2008 Jun 09; 16(12):8406-20. PubMed ID: 18545554.
    Abstract:
    An alternative optical coherence tomography (OCT) to clinical ophthalmic 830 nm spectral-domain OCTs (SD-OCT) is demonstrated. An axial resolution of 7.4 microm, ranging depth of 4.2 mm in tissue, sensitivity of 98.5 dB, and detection speed of 38,300 axial scans/s have been achieved. These are comparable or superior to those of recently commercially available ophthalmic 830 nm SD-OCTs in clinics. In addition, fast volumetric imaging for the in vivo human posterior eye with high-contrast of the choroid is achieved. A broadband 1.04 microm light source enables the high-contrast and high resolution imaging of the retina and choroid. The ranging depth is extended by applying a full-range imaging method with an electro-optic modulator (BM-scan method). A prototype high-speed InGaAs line scan camera with 1024 pixels is used. A newly reported sensitivity improvement property of the BM-scan method demonstrates a sensitivity enhancement of 5.1 dB. We also introduce a newly developed resampling calibration method of spectrum that is independent of the intrinsic dispersion mismatch of the interferometer. The three-dimensional structure of the in vivo human optic nerve head with a very deep cupping is successfully visualized.
    [Abstract] [Full Text] [Related] [New Search]