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  • Title: [Carcinosarcoma arising from a preexisting pleomorphic adenoma--true malignant mixed tumor of the parotid gland].
    Author: Nowak K.
    Journal: Otolaryngol Pol; 2007; 61(6):1024-7. PubMed ID: 18546958.
    Abstract:
    UNLABELLED: Carcinosarcoma (true malignant mixed tumor) is rare in salivary gland neoplasms. Even rarer is a carcinosarcoma arising from a preexisting pleomorphic adenoma. CASE: a 49-year-old woman was admitted with left neck pain. Computed tomography and USG-examination revealed a mass originating from left parotid gland. The patient undergone total parotidectomy with facial nerve preservation and then irradiation and chemioteraphy. Clinical and histologic date revealed it had developed from a preexisting pleomorphic adenoma. CONCLUSION: microscopic examination showed and neoplasm comprised of sarcomatous and carcinomatous cells. This tumor seemed to consist of two histogenetically different populations of cells. We also review the literature and dicuss the histogenetic origin of the carcinosarcoma of salivary gland.
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