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Title: Exposure of Vicia faba and Pisum sativum to copper-induced genotoxicity. Author: Souguir D, Ferjani E, Ledoigt G, Goupil P. Journal: Protoplasma; 2008 Nov; 233(3-4):203-7. PubMed ID: 18548320. Abstract: The potential genotoxicity of Cu(2+) was investigated in Vicia faba and Pisum sativum seedlings in hydroponic culture conditions. Cu(2+) caused a dose-dependent increase in micronuclei frequencies in both plant models. Cytological analysis of root tips cells showed clastogenic and aneugenic effects of this heavy metal on V. faba root meristems. Cu(2+) induced chromosomal alterations at the lowest concentration used (2.5 mM) when incubated for 42 h, indicating the potent mutagenic effect of this ion. A spectrum of chromosomal abnormalities was observed in V. faba root meristems, illustrating the genotoxic events leading to micronuclei formation.[Abstract] [Full Text] [Related] [New Search]