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  • Title: Significant differences in drug susceptibility among species in the Candida parapsilosis group.
    Author: van Asbeck E, Clemons KV, Martinez M, Tong AJ, Stevens DA.
    Journal: Diagn Microbiol Infect Dis; 2008 Sep; 62(1):106-9. PubMed ID: 18555634.
    Abstract:
    Candida parapsilosis family has 3 proposed species: C. parapsilosis sensu stricto, Candida orthopsilosis, and Candida metapsilosis. C. parapsilosis sensu stricto had significantly higher caspofungin (CAS) and anidulafungin MICs than C. orthopsilosis or C. metapsilosis; C. metapsilosis was least susceptible to fluconazole. C. parapsilosis sensu stricto more frequently displayed (37%) paradoxical growth in CAS (P < or = 0.02). These species susceptibility differences could affect therapeutic choices.
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