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  • Title: Facial cleft and associated anomalies: incidence among infants at a Jordanian medical centre.
    Author: Aqrabawi HE.
    Journal: East Mediterr Health J; 2008; 14(2):356-9. PubMed ID: 18561727.
    Abstract:
    To estimate incidence of cleft lip and cleft palate among Jordanian infants and to identify associated anomalies, we carried out a prospective, hospital-based study over a 5-year period, January 2000-January 2005. The total number of liveborn infants was 25 440, 60 of whom (2.4/1000) had facial clefts: 20 (33%) with cleft lip, 15 (25%) with cleft palate and 25 (42%) with both. Congenital heart disease was the commonest associated anomaly (47%) identified, followed by skeletal abnormalities (13%). Renal anomalies were found in 10% of cases. The high prevalence of congenital heart disease may justify routine echocardiography screening. The high consanguineous marriage rate may be a contributing factor to the high incidence of cleft anomalies.
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