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  • Title: Chemoembolization of hepatic metastases from ocular melanoma: assessment of response with contrast-enhanced and diffusion-weighted MRI.
    Author: Buijs M, Vossen JA, Hong K, Georgiades CS, Geschwind JF, Kamel IR.
    Journal: AJR Am J Roentgenol; 2008 Jul; 191(1):285-9. PubMed ID: 18562760.
    Abstract:
    OBJECTIVE: The purpose of this study was to assess the utility of assessment of tumor size and enhancement with diffusion-weighted and conventional MRI in the evaluation of response to transarterial chemoembolization therapy for metastatic ocular melanoma. CONCLUSION: In patients with ocular melanoma and liver metastasis treated with transarterial chemoembolization, functional MRI showed significant changes in the lesions. These changes included a decrease in tumor enhancement and an increase in the apparent diffusion coefficient of the tumor, suggesting increasing tumor necrosis and cell death.
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