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  • Title: Binding of the BL/VL3 murine T cell lymphoma to radiation leukaemia virus is specific for viral env determinants.
    Author: O'Neill HC.
    Journal: J Gen Virol; 1991 Jul; 72 ( Pt 7)():1725-8. PubMed ID: 1856699.
    Abstract:
    Molecularly cloned radiation leukaemia viruses (RadLVs) isolated from the BL/VL3 radiation-induced thymoma have been used in assays to compare the binding specificity of the BL/VL3 cell line for different retroviruses. BL/VL3 cells bound well to two of three thymotropic, leukaemogenic viruses produced by this cell line. BL/VL3 did not bind to a cloned fibrotropic, non-leukaemogenic RadLV. BL/VL3 appears to have receptor specificity for only some of the leukaemogenic RadLVs, and this appears to be related to differences in the viral env sequence.
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