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  • Title: Recurrent myasthenia gravis due to a pleural implant 3 years after radical thymectomy.
    Author: Heyman SR, De Raeve H, Mercelis R, De Pooter C, Van Schil P.
    Journal: Ann Thorac Surg; 2008 Jul; 86(1):299-301. PubMed ID: 18573446.
    Abstract:
    Although recurrence of a thymoma is rare, pleural dissemination or local relapses have been described. We present a patient who underwent complete thymectomy for a thymoma, type AB according to the World Health Organization classification and stage II according to Masaoka, followed by adjuvant radiotherapy. Three years later, a relapse of the myasthenic symptoms occurred. An isolated pleural implant above the left diaphragm was removed by video-assisted thoracoscopy. Pathology confirmed the recurrence of the thymoma. As this is a rare occurrence, no precise therapeutic guidelines exist. In our case, surgical resection of the recurrence with adjuvant immunomodulating therapy for myasthenia provided good results.
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