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Title: [Isolation and identification of major steroidal saponins of Paris polyphylla Smith var stenophylla Franch]. Author: Yin HX, Xue D, Bai N, Chen C, Chen Y, Zhang H. Journal: Sichuan Da Xue Xue Bao Yi Xue Ban; 2008 May; 39(3):485-8. PubMed ID: 18575349. Abstract: OBJECTIVE: To research the steroidal saponins of Paris polyphylla Smith var stenophylla Franch for enriching the resource of Radix Paridis. METHODS: Compounds were isolated by silica gel, macroporous adsorption resin,Sephadex LH-20 and RP-C18 column chromatography and the structures were elucidated on the basis of spectroscopic methods. RESULTS: Five kinds of steroidal saponins were isolated and identified as follows: paris saponin I (1) Diosgenin-3-O-alpha-L-rhamnopyranosyl-(1 --> 2)-[alpha-L-arabinofuranosyl-(1 --> 4 )]-beta-D-Glucopyranoside, paris saponin V (2) Diosgenin-3-O-alpha-L-rhamnopyranosyl-(1 --> 2)-beta-D-glucopyranoside, paris saponin VI (3) Pennogenin-3-O-alpha-L-rhamnopyranosyl-(1 --> 2)-beta-D-glucopyranoside, paris saponin VII (4) Pennogenin-3-O-alpha-L-rhamnopyranosyl-(1 --> 4)-alpha-L-rhamnopyranosyl- 1 --> 4)-[alpha-L-rh-amnopyranosyl-(1 --> 2)]-beta-D-glucopyranoside, paris saponin H (5) Pennogenin-3-O-alpha-L-rhamnopyranosyl-(1 --> 2)-[alpha-L-arabinofuranosyl-(1 --> 4)]-beta-D-Glucopyranoside. CONCLUSION: All the five kinds of steroidal saponins were isolated from P. polyphylla. Smith var stenophylla Franch for the first time.[Abstract] [Full Text] [Related] [New Search]