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  • Title: Coarctation of the aorta presenting as systemic hypertension in a young adult.
    Author: Alegria JR, Burkhart HM, Connolly HM.
    Journal: Nat Clin Pract Cardiovasc Med; 2008 Aug; 5(8):484-8. PubMed ID: 18578006.
    Abstract:
    BACKGROUND: A 20-year-old male presented with a history of systemic hypertension. Examination revealed a systolic murmur with an early ejection click, and femoral pulses were markedly reduced. INVESTIGATIONS: Physical examination, laboratory testing, electrocardiography, chest radiography, comprehensive echocardiography including pulsed-wave Doppler examination, and CT of the chest. DIAGNOSIS: Severe coarctation of the juxtaductal aorta accompanied by an ascending aortic aneurysm, a bicuspid aortic valve without evidence of hemodynamically significant stenosis or regurgitation, and an atrial septal defect. MANAGEMENT: An ascending-descending intrapericardial aortic bypass graft, atrial septal defect closure, and ascending aorta replacement were all successfully performed. Lifelong follow-up will be required.
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