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  • Title: [Study of expired air plateau period by oral administration of 13C-leucine during feeding state].
    Author: Tian Y, Piao J, Gou L, Tian Y, et al.
    Journal: Wei Sheng Yan Jiu; 2008 Mar; 37(2):187-9. PubMed ID: 18589604.
    Abstract:
    OBJECTIVE: To explore the expired air plateau period by oral administration of 13C-Leucine during feeding state in study of amino acid metabolism kinetics. METHODS: Six healthy adult women were selected as subjects, 13C-leucine was orally administrated for 4 hours during feeding state on day 6 after 5 days of adaptation period. The expired air was collected during the course of administration and 1 hour after the end of administration to determine the delta over baseline for 13C. RESULTS: The delta over baseline for 13C in expired air was steady at a higher level during period of half hour before and after the end of administration respectively. CONCLUSION: It was suggested that half hour before and after the end of administration respectively was the optimal period for sampling in the study of metabolism kinetics of amino acid by oral administration of 13C-leucine during feeding state.
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