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  • Title: [Study on the antimutagenicity of Cordyceps taii polysaccharide].
    Author: Peng KJ, Liu JL.
    Journal: Zhong Yao Cai; 2008 Jan; 31(1):86-8. PubMed ID: 18589757.
    Abstract:
    OBJECTIVE: To study the antimutagenicity of Cordyceps taii polysaccharide (CDPl). METHODS: Ames test and micronucleus form assay of polychromatic erythrocytes in mice bone marrow were used to evaluate the antimutagenic effect of CDPI with different concentrations. RESULTS: CDP1 could inhibit the reverse mutation on Salmonella typhimuriun strains TA97, TA98, TA100 and TA102 without S9 in different degree, especially remarkable in the strains T97 ,T98 and T102. The maxium inhibition rates of strains TA97, TA98, TA100 and T102 were 68.5%, 79.5%,19. 8% and 81.3%, respectively. In addition, CDPI could significantly reduce micronucleus frequencies induced by cyclophosphamide, and the rate of maxium inhibition was 70.3%. CONCLUSION: Cordyceps taii polysaccharide possesses significantly antimutagenic properties.
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