These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Bioactive brominated metabolites from the Red Sea sponge Pseudoceratina arabica.
    Author: Badr JM, Shaala LA, Abou-Shoer MI, Tawfik MK, Habib AA.
    Journal: J Nat Prod; 2008 Aug; 71(8):1472-4. PubMed ID: 18598078.
    Abstract:
    Chemical investigation of the Red Sea sponge Pseudoceratina arabica has led to the isolation and identification of seven brominated compounds including two new bromotyramine derivatives, hydroxymoloka'iamine (2) and moloka'iakitamide (6), and a new brominated phenolic compound, ceratinophenol A (5), together with the known compounds moloka'iamine (1), ceratinamine (3), 5-bromo-2,3-dihydroxy-6-methoxybenzaldehyde (4), and psammaplysin-A (7). Biological evaluation of these metabolites indicated that moloka'iamine and moloka'iakitamide possess significant parasympatholytic effects on isolated rabbit heart and jejunum. This finding has important implications for further biological investigation of this class of compounds. Moreover, these compounds showed weak antibacterial and antifungal activities.
    [Abstract] [Full Text] [Related] [New Search]