These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Effects of allopurinol on beer-induced increases in plasma concentrations of purine bases and uridine.
    Author: Inokuchi T, Ka T, Yamamoto A, Takahashi S, Tsutsumi Z, Moriwaki Y, Yamamoto T.
    Journal: Nucleosides Nucleotides Nucleic Acids; 2008 Jun; 27(6):601-3. PubMed ID: 18600512.
    Abstract:
    We investigated the effects of allopurinol on beer-induced changes in the plasma concentration and urinary excretion of purine bases. Five healthy subjects underwent three studies: ingestion of beer after taking 300 mg allopurinol (combination study); ingestion of beer alone; ingestion of allopurinol alone. Increased plasma concentrations and urinary excretion of hypoxanthine were greater in the combination study than the beer alone study. However, increases in total plasma purine base concentrations were greater in the beer alone study, even though increases in plasma uridine concentrations did not differ. Beer-induced increases in plasma concentrations of purine bases appear partially offset by increased urinary excretion of hypoxanthine after allopurinol, which also controls increases in plasma uric acid levels caused by alcoholic beverage ingestion.
    [Abstract] [Full Text] [Related] [New Search]