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  • Title: Clinical effect and mechanism of cariostatic action of fluoride-containing toothpastes: a review.
    Author: Rølla G, Ogaard B, Cruz Rde A.
    Journal: Int Dent J; 1991 Jun; 41(3):171-4. PubMed ID: 1860724.
    Abstract:
    Caries reduction has been observed in certain parts of the western world. The reduction coincides with the timing of the introduction of fluoride-containing toothpastes and no other factors can explain the caries reduction. It is possible that improved oral hygiene and use of fluoride have a synergistic effect.
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