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Title: Antimicrobial diterpenes from Trigonostemon chinensis. Author: Yin S, Su ZS, Zhou ZW, Dong L, Yue JM. Journal: J Nat Prod; 2008 Aug; 71(8):1414-7. PubMed ID: 18611050. Abstract: Five new diterpenes, trigonochinenes A-E (1-5), and two known ones, 3,4- seco-sonderianol (6) and 3,4- seco-sonderianic acid (7), were isolated from the aerial part of Trigonostemon chinensis. Compounds 1-4 possess a rare 3,4-seco-cleistanthanic skeleton, and compound 5 is a highly aromatized tetranorditerpene. Structures of these compounds were elucidated by spectroscopic analysis. The antimicrobial activities of compounds 1-7 were evaluated against a panel of bacteria and fungi.[Abstract] [Full Text] [Related] [New Search]