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  • Title: Enabling continuous-flow chemistry in microstructured devices for pharmaceutical and fine-chemical production.
    Author: Kockmann N, Gottsponer M, Zimmermann B, Roberge DM.
    Journal: Chemistry; 2008; 14(25):7470-7. PubMed ID: 18613163.
    Abstract:
    Microstructured devices offer unique transport capabilities for rapid mixing, enhanced heat and mass transfer and can handle small amounts of dangerous or unstable materials. The integration of reaction kinetics into fluid dynamics and transport phenomena is essential for successful application from process design in laboratory to chemical production. Strategies to implement production campaigns up to tons of pharmaceutical chemicals are discussed, based on Lonza projects.
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