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  • Title: Malignancy after solid organ transplantation: an overview.
    Author: Zafar SY, Howell DN, Gockerman JP.
    Journal: Oncologist; 2008 Jul; 13(7):769-78. PubMed ID: 18614590.
    Abstract:
    With improving survival following solid organ transplantation, clinicians must be aware of post-transplant complications. One increasingly frequent complication is the development of malignancy after transplantation. The most common malignancies encountered in the post-solid organ transplant setting are nonmelanoma skin cancers, post-transplant lymphoproliferative disorders, and Kaposi's sarcoma (KS). The pathogenesis of these tumors is likely related to the immunosuppressive drugs used post-transplantation and subsequent viral infection. Treatment involves modification of the immunosuppressive drug regimen, resection of localized disease, and chemotherapy. We present the second reported case of a patient with lung transplantation who developed KS in the lung graft.
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