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  • Title: Synthesis, spectral analysis, antibacterial and antifungal activities of some 4,6-diaryl-4,5-dihydro-3-hydroxy-2[H]-indazole-a novel fused indazole derivative.
    Author: Gopalakrishnan M, Sureshkumar P, Thanusu J, Kanagarajan V.
    Journal: J Enzyme Inhib Med Chem; 2008 Dec; 23(6):974-9. PubMed ID: 18615281.
    Abstract:
    A novel class of 4,6-diaryl-4,5-dihydro-3-hydroxy-2[H]-indazoles 25-32 were synthesized and evaluated for their in vitro antibacterial and antifungal activities. Four Compounds, which all possessed electron withdrawing functional groups (-Cl, -NO(2), -Br) 27, 28, 30 and 32 were more potent against the tested bacterial/fungal strains than the standard bacterial and fungal drugs ciprofloxacin and fluconazole respectively.
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