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  • Title: Bone mineral density changes after total knee arthroplasty: one-year follow-up.
    Author: Gazdzik TS, Gajda T, Kaleta M.
    Journal: J Clin Densitom; 2008; 11(3):345-50. PubMed ID: 18619880.
    Abstract:
    The study involved analysis of differences in bone mineral density (BMD) in the region of knee arthroplasty in 106 female patients. BMD was assessed using dual-energy X-ray absorptiometry in a follow-up time schedule: before surgery and 2 weeks postoperatively (baseline), 5, 12, 24, and 48 weeks after knee joint arthroplasty. Four assessment regions A, B, C, and D were determined in immediate proximity to the arthroplasty site. A year after surgery, a decrease in BMD was observed in all determined regions-(9.9%, 13.8%, 9.9%, and 7.6% respectively) in comparison with the baseline value. The most significant BMD decrease was observed in the period between 5 and 12 weeks after the knee joint arthroplasty. In our opinion, the decrease in BMD at the knee joint arthroplasty site is a result of the postoperative increased bone resorption and decreased patient motor activity.
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