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  • Title: [Correction with T-activin of secondary immunodeficiency in inflammatory diseases of female internal genital organs].
    Author: Pogodin OK, Samorodinova LA, Matveeva NK, Sukhikh GT.
    Journal: Akush Ginekol (Mosk); 1991 Apr; (4):40-4. PubMed ID: 1862873.
    Abstract:
    A clinicoimmunological examination was performed in 70 patients with acute inflammatory disease of internal genitalia. All the patients received a multimodality anti-inflammatory therapy. They were divided into 2 groups: 1) 30 patients taking ++T-activin as an adjuvant and 2) 40 patients untreated with it. T and B lymphocytes were measured by current cytofluorometry+ by means of monoclonal antibodies and the rosette-forming method. A subpopulation analysis of the T-cell immune system revealed lower T-helper count and decreased immunoregulatory index. ++T-activin used in the multimodality therapy for acute inflammatory diseases of internal genitalia improved the qualitative parameters of regulatory T-cell subpopulations, returned T and B lymphocytes to normal levels and elevated IgG concentrations.
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