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  • Title: Direct acylation of aryl bromides with aldehydes by palladium catalysis.
    Author: Ruan J, Saidi O, Iggo JA, Xiao J.
    Journal: J Am Chem Soc; 2008 Aug 13; 130(32):10510-1. PubMed ID: 18636731.
    Abstract:
    A new protocol for the direct acylation of aryl bromides with aldehydes is established. It appears to involve palladium-amine cooperative catalysis, affording synthetically important alkyl aryl ketones in moderate to excellent yields in a straightforward manner, and broadening the scope of metal-catalyzed coupling reactions.
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