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  • Title: Histochemistry of oxidative enzymes in experimental allergic encephalomyelitis.
    Author: Wender M, Kozik M, Goncerzewicz A.
    Journal: Folia Histochem Cytochem (Krakow); 1976; 14(3):173-80. PubMed ID: 186370.
    Abstract:
    The histoenzymic pattern of oxidative enzymes (G3PD, IDH, SD, G6PD,HBD, NADPH: dehydrogenase) was investigated in experimental allergic encephalomyelitis (EAE) produced in rats according to PATERSON [13]. The results obtained lead to following conclusions: (1) The neuroglia, including the white matter oligodendroglia of immunized rats, exhibits increased oxidoreductase activities; (2) The neuroallergic reaction induces some stimulation of the oxidoreductive metabolism of oligoden-droglia; (3) The enzymatic hyperactivity in EAE does not show any relation to the morphological signs of alterations of the myelin sheath.
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